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Owen Farrell and Joe Marchant will fill England’s midfield with Marcus Smith at flyhalf in their Six Nations opener against Scotland on Saturday as Manu Tuilagi was omitted from the matchday squad announced by Steve Borthwick on Thursday.

When fit, Tuilagi has been one of the first names on the team sheet since his debut in 2011 but he has struggled to show his usual impact at Sale this season, opening the door for the return of Marchant.

The centre is due to leave Harlequins to join Stade Francais next season and so will not be eligible for England after the World Cup but new coach Borthwick’s hand was forced somewhat by injuries to Henry Slade, Elliot Daly and Dan Kelly.

The only time Smith, Farrell and Marchant have played together for England was in the 30-28 defeat to Australia in the first of a three-test series in Perth in July 2022 — after which Marchant was dropped and subsequently overlooked by former coach Eddie Jones.

Max Malins, another player recalled by Borthwick after being discarded by Jones despite topping the Premiership try-scoring charts last season, starts on the right wing.

London Irish’s Ollie Hassell-Collins will make his international debut on the left. Freddie Steward is at fullback, with Jack van Poortvliet starting at scrumhalf ahead of Leicester team mate Ben Youngs.

In the back row Ben Curry will make his first England start, after a replacement appearance in 2021, and Lewis Ludlam will play at number six with Alex Dombrandt at number eight.

Ollie Chessum will partner Maro Itoje at lock with Nick Isiekwe on the bench. Meanwhile prop Dan Cole, whose last appearance was in the 2019 World Cup final defeat to South Africa, is also on the bench.

“Marcus and Owen is the right combination for this game and Joe Marchant at 13 works really well with Marcus,” Borthwick told reporters. “You see how those two connect, both will ball in hand and the great attacking kicks that Marcus has and the way Joe finds those.

“Some of England’s best performances have been with Owen in the 12 shirt and he has talked to me in the past about how he enjoys playing with other ball players.

“Ollie Lawrence has played tremendously well this season and we are excited about seeing him out there again because he is a player who has not been in the international environment for a year or two. He has power, speed and athleticism,” he added.

England have lost three and drawn one of the last five Calcutta Cup meetings against their oldest rivals but are strong favourites to get their campaign off to a winning start at Twickenham.

England XV: Freddie Steward, Max Malins, Joe Marchant, Owen Farrell, Ollie Hassell-Collins, Marcus Smith, Jack van Poortvliet, Ellis Genge, Jamie George, Kyle Sinckler, Maro Itoje, Ollie Chessum, Lewis Ludlam, Ben Curry, Alex Dombrandt.

Replacements: Jack Walker, Mako Vunipola, Dan Cole, Nick Isiekwe, Ben Early, Ben Youngs, Ollie Lawrence, Anthony Watson.

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